Podoplanin Recombinant Antibody / gp36

It recognizes a muco-protein of 38-43kDa, which is identified as Podoplanin (PDPN), also called Glycoprotein 36 (Gp36). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

Q86YL7

Rabbit

A recombinant partial protein sequence (within amino acids 1-150) from the human protein was used as the immunogen for the Glycoprotein 36 antibody.

Monoclonal

IgG κ

Recombinant

ELISA, IF, IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Aliquot the Glycoprotein 36 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Glycoprotein 36 antibody is available for research use only.