Synaptophysin Recombinant Antibody

This recombinant mouse monoclonal antibody recognizes a protein of 38kDa that is identified as Synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

P08247

Mouse

A portion of amino acids 224-313 was used as the immunogen for the recombinant SYP antibody.

Monoclonal

IgG1 κ

Recombinant

IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Aliquot the recombinant SYP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This recombinant SYP antibody is available for research use only.