TAU Antibody

TAU/MAPT promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [UniProt]

P10636

Rabbit

A portion of amino acids 677-707 from the human protein was used as the immunogen for this TAU antibody.

Polyclonal

Ig

WB, IHC, IF, ELISA

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the TAU antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This TAU antibody is available for research use only.