CTnT Antibody / Cardiac Troponin T / TNNT2

Cardiac muscle troponin T (cTnT), is a protein which in humans is encoded by the TNNT2 gene. It is mapped to 1q32.1. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

P45379

Rabbit

Amino acids K88-K298 from the human protein were used as the immunogen for the Cardiac Troponin T antibody.

Polyclonal

IgG

WB, Direct ELISA

Purified

0.5mg/ml if reconstituted with 0.2ml sterile DI water

After reconstitution, the Cardiac Troponin T antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.