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EGF Receptor / EGFR Antibody
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
P00533
Mouse
A portion of amino acids 344-492 from the human protein was used as the immunogen for the EGFR antibody.
Monoclonal
IgG2b κ
IHC-P, WB
Purified
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Store the EGFR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
This EGFR antibody is available for research use only.
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