FGFR1 Antibody

FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.

P11362

Rabbit

This FGFR1 antibody was produced from rabbits immunized with a human His fusion protein.

Polyclonal

Ig

FACS, WB, IHC, ELISA

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the FGFR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This FGFR1 antibody is available for research use only.