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MDM2 Recombinant Antibody

CAT:V9675-100UGSize:100 µgPrice:Ask for quotation

Availability:

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Shipping:

This product ships without dry ice.

Description:

MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers.

UniProt:

Q00987

Host:

Rabbit

Immunogen:

A portion of amino acids 126-254 was used as the immunogen for the recombinant MDM2 antibody.

Clonality:

Monoclonal

Isotype:

IgG

Type:

Recombinant

Applications:

ELISA

Format:

Purified

Buffer:

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution:

Aliquot the recombinant MDM2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations:

This recombinant MDM2 antibody is available for research use only.

Supplier Category:

Primary antibody

Supplier URL:

http://www.nsjbio.com/tds/recombinant-mdm2-antibody-mdm2-7061r-v9675

Product Picture:

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