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Melanoma Cell Marker Antibody Cocktail (anti-MART-1 + gp100 + Tyrosinase)
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Q16655 (Melan-A), P14679 (Tyrosinase), P40967 (gp100)
Mouse
Recombinant MART-1 protein (M2-7C10 & M2-9E3), recombinant tyrosinase protein (T311) and extract of pigmented melanoma metastases from lymph nodes (HMB45) were used as the immunogens for this Melanoma Cell Marker antibody cocktail.
Monoclonal
IgG1 + IgG2a + IgG2b + IgG2b
IHC-P, WB
Purified
1 mg/ml in 1X PBS; BSA free, sodium azide free
Store the Melanoma Cell Marker antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
This Melanoma Cell Marker antibody cocktail is available for research use only.
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