Tenascin C Antibody

In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this mAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

P24821

Mouse

Human breast carcinoma cells were used as the immunogen for the Tenascin C antibody.

Monoclonal

IgG1 κ

IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Store the Tenascin C antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Tenascin C antibody is available for research use only.