Kappa Light Chain Recombinant Antibody

This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

P01601, P01834

Rabbit

Recombinant human Ig kappa chain was used as the immunogen for this recombinant Kappa light chain antibody.

Monoclonal

IgG κ

Recombinant

IHC-P

Purified

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Store the recombinant Kappa light chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This recombinant Kappa light chain antibody is available for research use only.