Phospho-Src Antibody (pY215)

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-Src kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. Transcript Variant: This variant (1) represents the longer transcript. Both isoforms 1 and 2 encode the same protein.

P12931

Rabbit

This phospho-Src antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY215 of human Src.

Polyclonal

Ig

WB, ELISA

Antigen affinity purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the phospho-Src antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This phospho-Src antibody is available for research use only.