Integrin alpha 3 Antibody

ITGA3 (Integrin alpha 3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. It is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. It is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of the human protein increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, two potential cleavage sites, and the the N-terminal repeating units characteristic of ITGAs.

P26006

Rabbit

An amino acid sequence from the N-terminus of human ITG3A (LFGYSVALHRQTERQQR) was used as the immunogen for this Integrin alpha 3 antibody (100% homologous in human, mouse and rat).

Polyclonal

IgG

WB, IHC-P

Antigen affinity purified

0.5mg/ml if reconstituted with 0.2ml sterile DI water

After reconstitution, the Integrin alpha 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

This Integrin alpha 3 antibody is available for research use only.