Beta Catenin Antibody

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]

P35222

Mouse

Chicken b-Catenin was used as the immunogen for the b-Catenin antibody.

Monoclonal

IgG1 κ

FACS, IF, WB

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Store the b-Catenin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This b-Catenin antibody is available for research use only.