Beta Tubulin Antibody / TUBB3

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance. Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Plays a role in dorsal root ganglion axon projection towards the spinal cord. [UniProt]

Q13509

Mouse

Amino acids 437-450 were used as the immunogen for the Beta Tubulin antibody.

Monoclonal

IgG1 κ

IHC-P, WB

Purified

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Store the Beta Tubulin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Beta Tubulin antibody is available for research use only.