Bax Antibody

BCL2 associated X protein/Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. [UniProt]

Q07812

Mouse

Recombinant full-length human protein was used as the immunogen for the Bax antibody.

Monoclonal

IgG1

IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Store the Bax antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Bax antibody is available for research use only.