Beta Arrestin 2 Antibody

Beta Arrestin 2 is an intracellular protein that in humans is encoded by the ARRB2 gene. Members of the arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals, as well as having signalling roles in their own right. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptorfunction in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Beta-arrestins were originally discovered in the context of heterotrimeric G protein-coupled receptor desensitization, but they also function in internalization and signaling of these receptors.

P32121

Rabbit

An amino acid sequence from the C-terminus of human ARRB2 (RLKGMKDDDYDDQLC) was used as the immunogen for this Beta Arrestin 2 antibody.

Polyclonal

IgG

WB, IHC-P

Antigen affinity purified

0.5mg/ml if reconstituted with 0.2ml sterile DI water

After reconstitution, the Beta Arrestin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

This Beta Arrestin 2 antibody is available for research use only.