Inhibin alpha Antibody / INHA

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

P05111

Rabbit

A portion of amino acids 79-108 from the human protein was used as the immunogen for the Inhibin alpha antibody.

Polyclonal

Ig

WB, FACS, IHC-P, IF

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the Inhibin alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Inhibin alpha antibody is available for research use only.