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CD86 Antibody

CAT:V7172-100UGSize:100 µgPrice:Ask for quotation

Availability:

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Shipping:

This product ships with dry ice.

Description:

CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is a receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. [UniProt]

UniProt:

P42081

Host:

Mouse

Immunogen:

Recombinant human full-length protein was used as the immunogen for the CD86 antibody.

Clonality:

Monoclonal

Isotype:

IgG1 κ

Applications:

WB, IHC-P

Format:

Purified

Buffer:

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution:

Store the CD86 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations:

This CD86 antibody is available for research use only.

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