Anti-Hu TCR Vgamma9 PE

TCR Vgamma9 is a variant of TCR gamma chain, that is present on a subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 T cells are able to recognize and kill various tumor cells, as this receptor heterodimer binds to certain phosphoantigens, expressed by tumors.

The mouse monoclonal antibody B3 recognizes an extracellular epitope of human TCR Vgamma9, a variant of TCR gamma chain, which is expressed on a gamma/delta T cell subpopulation with cytolytic activity against various tumor cells.

RUO

Mouse

Human,Non-human primates

human T cells

TCR Vgamma9

IgG1

B3

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 mL) is sufficient for 100 tests.

FC

PE

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

*van Rhijn I, van den Berg LH, Ang CW, Admiraal J, Logtenberg T: Expansion of human gammadelta T cells after in vitro stimulation with Campylobacter jejuni. Int Immunol. 2003 Mar15(3):373-82., URL: https://pubmed.ncbi.nlm.nih.gov/12618481/,

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.