Cadherin 10 Antibody / CDH10

CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.

Q9Y6N8

Rabbit

A portion of amino acids 495-523 from the human protein was used as the immunogen for the Cadherin 10 antibody.

Polyclonal

Ig

WB, FACS, IHC-P

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the Cadherin 10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Cadherin 10 antibody is available for research use only.