Angiotensin II Type 1 Receptor Antibody / AGTR1 / AT1R

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].

P30556

Rabbit

A portion of amino acids 211-240 from the human protein was used as the immunogen for the Angiotensin II Type 1 Receptor antibody.

Polyclonal

Ig

IHC-P, WB, FACS, IF

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the Angiotensin II Type 1 Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Angiotensin II Type 1 Receptor antibody is available for research use only.