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STAT3 Antibody

CAT:F52478-0.08MLSize:0.08 mLPrice:Ask for quotation

Availability:

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Shipping:

This product ships with dry ice.

Description:

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).

UniProt:

P40763

Host:

Mouse

Immunogen:

This STAT3 antibody was produced from a mouse immunized with a recombinant protein from human.

Clonality:

Monoclonal

Isotype:

IgG2a κ

Applications:

WB, ELISA

Format:

Purified

Buffer:

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution:

Aliquot the STAT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations:

This STAT3 antibody is available for research use only.

Product Picture:

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