Caldesmon / CAD Antibody HMW

Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.

Q05682

Mouse

Crude human uterus extract was used as the immunogen for the Caldesmon antibody.

Monoclonal

IgG1 κ

IHC-P, WB

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the Caldesmon antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Caldesmon antibody is available for research use only.