Anti-14-3-3 Sigma / Stratifin(CPTC-SFN-2), CF647 conjugate

Stratifin is a p53-induced tumor suppressor gene which is activated in response to DNA damage, causing cell cycle arrest at G2 phase by blocking cdc2-cyclin B1 complex from entering the nucleus. It is inactivated in breast, lung, prostate, liver and gastric cancer. It is associated with poor prognosis when its down-regulation is observed in epithelial ovarian cancer. SFN expression could contribute to cancer cell proliferation and the development and/or progression of human gastrointestinal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Stratifin; YWHAS

41116161

Primary and secondary antibodies for multiple methodology
immunostaining detection application

SFN

2810

523718

P31947

Cytoplasmic

Mouse

Human

Recombinant human full-length SFN protein

14-3-3 Sigma | Stratifin

Monoclonal

IgG1 κ

CPTC-SFN-2

CF647

Animal

IHC, FFPE (verified) | WB (verified)

IHC, FFPE, WB

PC-3 cells, Skin and tissues enriched in stratified squamous keratinizing epithelium. HaCaT, hTCEpi, A-431 cell lines.

0.1 mg/mL

PBS, 0.1% BSA, 0.05% azide

28 kDa

Room temperature

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

2 years

Primary

https://biotium.com/product/14-3-3-sigma-stratifin-monoclonal-mouse-antibody-cptc-sfn-2