Anti-AIF1 / Iba1 (Microglia Marker) (AIF1/1909)

Allograft Inflammatory Factor 1 (also known as AIF1 or IBA1) is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC)._x000D_
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Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_
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Allograft inflammatory factor 1; AIF1; IBA1

41116161

Primary and secondary antibodies for multiple methodology
immunostaining detection application

AIF1

199

76364

P55008

Cytoplasmic

Mouse

Human

Purified fragment of human recombinant AIF1 protein (around aa 1-146) (exact sequence is proprietary)

Allograft Inflammatory Factor 1

Monoclonal

IgG1 κ

AIF1/1909

Purified, with BSA

Animal

IHC, FFPE (verified)

IHC, FFPE

Immunology

Lymph Node, Tonsil or Kidney

0.2 mg/mL

PBS, 0.05% BSA, 0.05% azide

17 kDa

Room temperature

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

2 years

Primary

https://biotium.com/product/aif1-iba1-monoclonal-mouse-antibody-aif1-1909