Amphiregulin rabbit pAb

The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014],

AREG; SDGF; AREGB; Amphiregulin; AR; Colorectum cell-derived growth factor; CRDGF

374/727738

P15514

Membrane; Single-pass membrane protein.

Rabbit

Human, Rat, Mouse,

The antiserum was produced against synthesized peptide derived from the Internal region of human AREG/AREGB. AA range:91-140

Polyclonal

WB, ELISA

1 year

1 mg/mL

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

17kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.