DEF6 antibody

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor(GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2(T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling(By similarity).

Differentially expressed in FDCP 6 homolog (DEF-6)|IRF4-binding protein|DEF6|IBP

50619

Q9H4E7

Rabbit

Human, Mouse, Rat

differentially expressed in FDCP 6 homolog(Mouse)

DEF6

Polyclonal

IgG

ELISA, WB, IHC

Signal Transduction, Immunology

Immunogen affinity purified

WB: 1:500-1:2000; IHC: 1:20-1:200

≥95% as determined by SDS-PAGE

Liquid

74 kDa

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Primary Antibodies

https://www.fn-test.com/product/FNab02325/

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab02325(DEF6 Antibody) at dilution of 1:50

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab02325 (DEF6 Antibody) at dilution of 1:600