MARCKSL1 antibody

Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems(By similarity).

MARCKS-related protein|MARCKS-like protein 1|Macrophage myristoylated alanine-rich C kinase substrate (Mac-MARCKS, MacMARCKS)|MARCKSL1|MLP|MRP

P49006

Rabbit

Human, Mouse, Rat

MARCKS-like 1

MARCKSL1

Polyclonal

IgG

ELISA, WB, IHC

Signal Transduction

Immunogen affinity purified

WB: 1:500-1:2000; IHC: 1:20-1:200

≥95% as determined by SDS-PAGE

Liquid

40-50 kDa

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Primary Antibodies

https://www.fn-test.com/product/FNab05010/

Immunohistochemistry of paraffin-embedded human lung cancer using FNab05010(MARCKSL1 antibody) at dilution of 1:50

Various lysates were subjected to SDS PAGE followed by western blot with FNab05010 (Marcksl1 antibody) at dilution of 1:500