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Axl rabbit pAb
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],
AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene
558
P30530
Cell membrane ; Single-pass type I membrane protein.
Rabbit
Human, Mouse, Rat
Synthesized peptide derived from Axl . at AA range: 640-720
Polyclonal
IHC, IF, ELISA
1 year
1 mg/mL
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
130kD
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
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