Beta Arrestin 1 Antibody / ARRB1

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.

P49407

Rabbit

A portion of amino acids 336-363 from the human protein was used as the immunogen for the ARRB1 antibody.

Polyclonal

Ig

FACS, IF, IHC-P, WB

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the ARRB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This ARRB1 antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/arrb1-antibody-f54630