Anti-Frataxin (Mitochondrial Marker)(rFXN/2124), CF740 conjugate

Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

CyaY; d-FXN; FARR; Frataxin mature form; Frataxin (81-210); FRDA; Friedreich ataxia protein; Fxn; i-FXN; m56-FXN; m78-FXN; m81-FXN; X25

41116161

Primary and secondary antibodies for multiple methodology
immunostaining detection application

FXN

2395

20685

Q16595

Mitochondria

Mouse

Human

Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)

Faxin

Recombinant Monoclonal

IgG1 κ

rFXN/2124

CF740

Animal

HepG2, HL-60 or HEK293 cells. Pancreas and Liver.

0.1 mg/mL

PBS, 0.1% rBSA, 0.05% azide

14 kDa

For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

Room temperature

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

2 years

Primary

https://biotium.com/product/frataxin-recombinant-monoclonal-mouse-antibody-rfxn-2124