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BMP-3A rabbit pAb

CAT:ES1777-01Size:50 μLPrice:Ask for quotation

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016],

Synonyms:

BMP3; BMP3A; Bone morphogenetic protein 3; BMP-3; Bone morphogenetic protein 3A; BMP-3A; Osteogenin

Gene ID:

651

UniProt:

P12645

Cellular Locus:

Secreted.

Host:

Rabbit

Species Reactivity:

Human,Rat,Mouse,

Immunogen:

The antiserum was produced against synthesized peptide derived from human BMP3. AA range:281-330

Clonality:

Polyclonal

Validated Applications:

WB,ELISA

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight:

55kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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Product Datasheet:

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