C-ets-2 Antibody / ETS2

ETS2 (Protein C-ets-2) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. ETS2 was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. ETS2 protein expression is complex and changes throughout development. ETS2 appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

P15036

Mouse

Recombinant full-length human ETS2 protein was used as the immunogen for the ETS2 antibody.

Monoclonal

IgG2b

ELISA, FACS, IF

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Aliquot the ETS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This ETS2 antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/ets2-antibody-pcrp-ets2-1d9-v8921