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CAR rabbit pAb

CAT:ES1837-01Size:50 μLPrice:Ask for quotation

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description:

The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. [provided by RefSeq, May 2011],

Synonyms:

CXADR; CAR; Coxsackievirus and adenovirus receptor; CAR; hCAR; CVB3-binding protein; Coxsackievirus B-adenovirus receptor; HCVADR

Gene ID:

1525

UniProt:

P78310

Cellular Locus:

[Isoform 1]: Cell membrane ; Single-pass type I membrane protein. Basolateral cell membrane ; Single-pass type I membrane protein. Cell junction, tight junction. Cell junction, adherens junction. In epithelial cells localizes to the apical junction complex composed of tight and adherens junctions (PubMed:12297051). In airway epithelial cells localized to basolateral membrane but not to apical surface (PubMed:11316797)..; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.

Host:

Rabbit

Species Reactivity:

Human,Mouse,Rat

Immunogen:

The antiserum was produced against synthesized peptide derived from human CXADR. AA range:1-50

Clonality:

Polyclonal

Validated Applications:

WB,ELISA

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight:

40kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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