CD27 Antibody

Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NF B and SAPK/JNK and induces apoptosis.

P26842

Mouse

A portion of amino acids 28-170 from the human protein was used as the immunogen for the CD27 antibody.

Monoclonal

IgG2c κ

IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the CD27 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This CD27 antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/cd27-antibody-lpfs2-4179-v8726