CFTR Recombinant Antibody / Cystic Fibrosis Transmembrane Regulator

CFTR functions as an ATP-gated anion channel, increasing the conductance for certain anions (e.g. Cl+/-) to flow down their electrochemical gradient. ATP-driven conformational changes in CFTR open and close a gate to allow transmembrane flow of anions down their electrochemical gradient.[5] This in contrast to other ABC proteins, in which ATP-driven conformational changes fuel uphill substrate transport across cellular membranes. Essentially, CFTR is an ion channel that evolved as a 'broken' ABC transporter that leaks when in open conformation. CFTR is found in the epithelial cells of many organs including the lung, liver, pancreas, digestive tract, and the reproductive tract. [Wiki]

P13569

Mouse

A recombinant human partial protein was used as the immunogen for this recombinant CFTR antibody.

Monoclonal

IgG1 κ

Recombinant

IHC-P

Purified

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Store the recombinant CFTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This recombinant CFTR antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/recombinant-cftr-antibody-rcftr-1342-v3552