CFTR Antibody / Cystic Fibrosis Transmembrane Regulator

Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

P13569

Mouse

Human recombinant protein was used as the immunogen for this CFTR antibody.

Monoclonal

IgG2a κ

IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the CFTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This CFTR antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/cftr-antibody-cftr1-1-v7216