Anti-TCL1 (T-Cell Marker) (TCL1/2747R), CF740 conjugate

T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

TCL1A; Lymphoma/leukemia, T-cell; Oncogene TCL1; P14 TCL1; T cell leukemia 1; T cell lymphoma 1; T cell lymphoma 1A;T-cell leukemia/lymphoma 1A; TCL1; TCL1A

41116161

Primary and secondary antibodies for multiple methodology
immunostaining detection application

TCL1A

10232

2484

P56279

Nucleus & cytoplasm

Rabbit

Human

Recombinant human TCL1 protein fragment (around aa 2-109) (exact sequence is proprietary)

TCL1

Recombinant Monoclonal

IgG

TCL1/2747R

CF740

Animal

IHC, FFPE (verified)

IHC, FFPE

Cancer, Immunology

Ramos or Raji cells. Tonsil or T-cell Lymphoma.

0.1 mg/mL

PBS, 0.1% rBSA, 0.05% azide

14 kDa

Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunohistology (formalin): 1-2 ug/mL for 30 minutes at RT|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes|Optimal dilution for a specific application should be determined by user

Room temperature

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

2 years

Primary

https://biotium.com/product/tcl1-recombinant-monoclonal-rabbit-antibody-tcl1-2747r