CSK22 rabbit pAb

Catalytic activity: ATP + a protein = ADP + a phosphoprotein. function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation. similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily. similarity: Contains 1 protein kinase domain. subunit: Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.

1459

P19784

Nucleus. Cytoplasm. Interaction with SIRT6 prevents translocation into the nucleus..

Rabbit

Human, Mouse

Synthesized peptide derived from part region of human protein

Polyclonal

WB, ELISA

1 year

1 mg/mL

WB 1:500-2000 ELISA 1:5000-20000

38kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.