Daprodustat (GSK1278863) is a HIF-prolyl hydroxylase inhibitor.Hypoxia stimulates erythropoietin (EPO) release through accumulation of hypoxia-inducible factor 1? (HIF-1?), resulting in an increase of erythrocyte production by the bone marrow.

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• Notes:FOR RESEARCH PURPOSES ONLY. NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.