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DC-LAMP rabbit pAb

CAT:ES8699-02Size:100 μLPrice:Ask for quotation

Availability:

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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This product ships without dry ice.

Description:

Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al. 1998 [PubMed 9768752]). [supplied by OMIM, Dec 2010],

Synonyms:

Lysosome-associated membrane glycoprotein 3 (LAMP-3;Lysosomal-associated membrane protein 3;DC-lysosome-associated membrane glycoprotein;DC LAMP;Protein TSC403;CD antigen CD208)

Gene ID:

27074

UniProt:

Q9UQV4

Cellular Locus:

Cell surface. Lysosome membrane ; Single-pass type I membrane protein. Cytoplasmic vesicle membrane ; Single-pass type I membrane protein. Early endosome membrane ; Single-pass type I membrane protein. During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3 (PubMed:9768752). Detected on lysosomes in mature dendritic cells (PubMed:9768752)..

Host:

Rabbit

Species Reactivity:

Human, Rat, Mouse,

Immunogen:

Synthetic peptide from human protein at AA range: 261-310

Clonality:

Polyclonal

Validated Applications:

WB, IHC, IF, ELISA

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000

Molecular Weight:

44kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Picture:

Product Datasheet:

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