Drebrin 1 Antibody

Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2); and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.

Q16643

Mouse

A recombinant human partial protein (amino acids 150-281) was used as the immunogen for the Drebrin 1 antibody.

Monoclonal

IgG1 κ

IHC-P, WB

Purified

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Store the Drebrin 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Drebrin 1 antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/drebrin-1-antibody-dbn1-3393-v7712