EDEM1 rabbit pAb

Function: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity. similarity: Belongs to the glycosyl hydrolase 47 family. subunit: Interacts with DERL2 and DERL3.

9695

Q92611

Endoplasmic reticulum membrane ; Single-pass type II membrane protein.

Rabbit

Human, Mouse

Synthesized peptide derived from part region of human protein

Polyclonal

WB, ELISA

1 year

1 mg/mL

WB 1:500-2000 ELISA 1:5000-20000

72kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.