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Etoposide
Etoposide inhibits the enzyme topoisomerase II, which unwinds DNA, and be doing so causes the DNA strand to break. Cancer cells are then less likely to be able to repair this damage (1).
Topoisomerase II inhibitor
(5S,5aR,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-β-D-glucopyranoside
33419-42-0
41116105
Synthetic
>98%
0.1
White solid
Soluble to 100 mM in DMSO
C29H32O13
588.56
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
1. Gordaliza M., et al. (2004) Toxicon. 44(4): 441-459.
Small Molecules
Inducer
https://www.stressmarq.com/products/small-molecules/etoposide-sih-244/
Canada
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