FAM48A rabbit pAb

Function: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail. similarity: Belongs to the FAM48 family. subunit: Interacts with MAPK14. tissue specificity: Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.

FAM48A C13orf19 FP757

55578

Q8NEM7

Nucleus.

Rabbit

Human, Mouse, Rat

The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A. AA range:231-280

Polyclonal

WB, ELISA

1 year

1 mg/mL

WB 1:500-2000, ELISA 1:10000-20000

85kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.