FAM48A rabbit pAb

Function: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail. similarity: Belongs to the FAM48 family. subunit: Interacts with MAPK14. tissue specificity: Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.

FAM48A C13orf19 FP757

55578

Q8NEM7

Nucleus.

Rabbit

Human,Mouse,Rat

The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A. AA range:231-280

Polyclonal

WB,ELISA

1 year

1 mg/mL

WB 1:500-2000, ELISA 1:10000-20000

85kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.