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FAM48A rabbit pAb
Function: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail. similarity: Belongs to the FAM48 family. subunit: Interacts with MAPK14. tissue specificity: Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.
FAM48A C13orf19 FP757
55578
Q8NEM7
Nucleus.
Rabbit
Human,Mouse,Rat
The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A. AA range:231-280
Polyclonal
WB,ELISA
1 year
1 mg/mL
WB 1:500-2000, ELISA 1:10000-20000
85kD
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
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