FAT1 rabbit pAb

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq, Jul 2008],

2195

Q14517

[Protocadherin Fat 1]: Cell membrane ; Single-pass type I membrane protein.; [Protocadherin Fat 1, nuclear form]: Nucleus.

Rabbit

Human,Rat,Mouse,

Synthesized peptide derived from human protein . at AA range: 1140-1220

Polyclonal

IHC,IF

1 year

1 mg/mL

IHC-p 1:50-300

504kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.