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Fibrinogen β rabbit pAb

CAT:ES5239-01Size:50 μLPrice:Ask for quotation

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description:

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014],

Synonyms:

FGB; Fibrinogen beta chain

Gene ID:

2244

UniProt:

P02675

Cellular Locus:

Secreted.

Host:

Rabbit

Species Reactivity:

Human, Rat, Mouse,

Immunogen:

Synthesized peptide derived from the Internal region of human Fibrinogen β.

Clonality:

Polyclonal

Validated Applications:

WB, ELISA

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight:

55kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet:

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