GDF-3 rabbit pAb

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],

GDF3; Growth/differentiation factor 3; GDF-3

9573

Q9NR23

Secreted. Cytoplasm. Mainly accumulated in the cytoplasm..

Rabbit

Human,Rat,Mouse,

Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360

Polyclonal

WB,ELISA

1 year

1 mg/mL

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

41kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.