GDF-6 rabbit pAb

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016],

GDF6; GDF16; Growth/differentiation factor 6; GDF-6; Growth/differentiation factor 16

392255

Q6KF10

Secreted.

Rabbit

Human,Mouse,Rat

The antiserum was produced against synthesized peptide derived from the Internal region of human GDF6. AA range:311-360

Polyclonal

WB,ELISA

1 year

1 mg/mL

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

50kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.